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KMID : 0670820100150010001
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Korean Journal of Medical Mycology
2010 Volume.15 No. 1 p.1 ~ p.11
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A Study on the Antimicrobial Effect of Bamboo (Phyllosrachys bambusoides) Essential Oil on Malassezia
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Lee Sook-Kyung
Byun Hee-Jin
Kim Myeung-Nam
Kim Beom-Joon
Hong Yu-Jin
Lim Yun-Young
Park Jong-Ho
Kim Youn-Tae
An Joo-Hee
Hwang Jae-Sung
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Abstract
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Background: Malassezia is considered as major factor in dandruff of human scalp. Objective: In order to develop an antimicrobial agent, bamboo oil was extracted by high temperture suction from dried bamboo truk abd then antimicrobial activities against Malassezia are investigated.
Methods: Minimum inhibitory concentration and antimicrobial activity were measured in Malassezia species.
Results: 1. Minimum inhibitory concentration of the Bamboo (Phyllosrachys bambusoides) Essential Oil Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standard, Malassezia dermatis patient were 10 μl/ml, 5 μl/ml, 5 μl/ml, 10 μl/ml, 5 μl/ml and 10 μl/ml respectively. 2. Minimum inhibitory concentration of the Itraconazole Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standardntia, Malassezia dermatis patient were 10 μg/ml, 10 μg/ml, 10 μg/ml, 0.1 μg/ml, 1 μg/ml, and 0.01 μg/ml, respectively. 3. Minimum inhibitory concentration of the ketoconazole Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standard, Malassezia dermatis patient were 0.01 μg/ml, 10 μg/ml, 10 μg/ml, 0.1 μg/ml, 0.01 μg/ml, and 0.01 μg/ml, respectively. 4. Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis patient and Malassezia dermatis patient showed the strongest antimicrobial effect on bamboo oil > ketoconazole > itraconazole. 5. Malassezia sympodialis standard, Malassezia sympodialis patient and Malassezia dermatis standard strongest antimicrobial effect on ketoconazole > bamboo oil > itraconazole.
Conclusion: Bamboo oil might be applied as antidandruff treatment modality by its anti-malassezial effect.
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KEYWORD
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Bamboo oil, Itraconazole, Ketoconazole, Minimum inhibitory concentration, Antimicrobial
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